Browsing by Author "Uma, S"
Now showing items 1-3 of 3
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Does diabetes mellitus affect the progress of tolerance to isosorbide dinitrate (ISDN) in corporal tissue?
Yildirim, S; Ayan, S; Sarioglu, Y; Gultekin, Y; Uma, S (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2000)For erection to take place, the penile arteries and sinusoids have to dilate, thereby increasing the blood flow into the penis. There is increasing evidence that release of L-arginine derived nitric oxide (NO) from ... -
Evidence of relaxant effect of omeprazole in rabbit corpus cavernosum in vitro
Sarioglu, Y; Yildirim, S; Utkan, T; Yildirim, MK; Uma, S (PERGAMON-ELSEVIER SCIENCE LTD, 2000)The present experiments were designed to investigate the effects of omeprazole, a H+-K+ ATPase inhibitor, on corporal smooth muscle tone in vitro. All spontaneous contractile activity in the corpus cavernosum was blocked ... -
Tolerance to isosorbide dinitrate in isolated strips of rabbit corpus cavernosum
Uma, S; Yildirim, S; Sarioglu, Y; Butuner, C; Yildirim, K (BLACKWELL SCIENCE LTD, 1998)The aim of this study was to investigate whether prolonged exposure to a high concentration of isosorbide dinitrate (ISDN) would result in tolerance being developed against its relaxant activity in strips of corpus cavernosum, ...